The Citric Acid Cycle begins with the formation of citric acid from acetyl CoA and oxaloacetic acid, followed by its conversion to -ketoglutaric acid (E). -ketoglutaric acid is then transformed into succinyl-CoA , leading to the formation of succinic acid, which subsequently converts to fumarate . Finally, fumarate is converted into malic acid and then into oxaloacetic acid , completing the cycle.

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